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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal UB AgroSup CNRS



Maître de Conférences CNU 64
Pôle : IPM
Equipe/Thème : Immunité et signalisation
Courriel :
Tel :
Fax :

Curriculum vitae

2010-present: Lecturer in Biochemistry, University of Burgundy, Dijon
 2009-2010: Postdoc at the Dept. of Plant Biology, University of Fribourg, Switzerland
 2008: PhD Thesis in Biochemistry, Cellular and Molecular Biology, University of Burgundy, Dijon
 2005: Master of Science Degree level 2 in Biochemistry, Cellular and Molecular Biology, University of Burgundy, Dijon

Activités de recherche

Identification of genes regulated by nitric oxide (NO) or proteins modified by S-nitrosylation in response to (a)biotic challenges
 Origin and role of NO in plant defense reactions against pathogens or in response to abiotic stresses
 Role of NO in iron homeostasis and in response to cadmium treatment
 Interplays between iron homeostasis and the priming mechanisms induced by beta-aminobutyric acid (BABA)
 Role of the pyoverdin siderophores produced by Pseudomonas fluorescens in plant defense reactions

Activités d’enseignement

Biochemistry courses in both the bachelor and master study programmes,in particular:
 - general biochemistry (structure of lipids, proteins, sugars and nucleic acids; replication; transcription; traduction) and enzymology (L1 and L2 levels)
 - Bioenergetics (L3 level)
 - Techniques used in analyses: gas-liquid (GC) chromatography, size-exclusion chromatography, protein electrophoresis (L3 level), High-Performance Liquid Chromatography (HPLC), spectrophotometry, fluorimetry (M1 level)

Mots clés

A. thaliana, nitric oxide (NO), plant defense reactions, pathogens, iron homeostasis, siderophores, priming


Koen E., Trapet P., Brulé D., Kulik A., Klinguer A., Atauri-Miranda L., Meunier-Prest R., Boni G., Glauser G., Mauch-Mani B., Wendehenne D. and Besson-Bard A. (2014) β-aminobutyric acid (BABA)-induced resistance in Arabidopsis thaliana: Link with iron homeostasis. Molecular Plant Microbe Interactions, 27: 1226-1240.
 Lamotte O., Bertoldo J.B., Besson-Bard A., Rosnoblet C., Aimé S., Hichami S., Terenzi H. and Wendehenne D. (2014) Protein S-nitrosylation: specificity and identification strategies in plants. Frontiers in Chemistry, 2:114.
 Trapet P., Kulik A., Lamotte O., Jeandroz S., Bourque S., Nicolas-Francès V., Rosnoblet C., Besson-Bard A. and Wendehenne D. (2014) NO signaling in plant immunity: A tale of messengers. Phytochemistry, doi: 10.1016/j.phytochem.2014.03.015.
 Koen E.*, Besson-Bard A.*, Duc C., Astier J., Gravot A., Richaud P., Lamotte O., Boucherez J., Gaymard F. and Wendehenne D. (2013) Arabidopsis thaliana nicotianamine synthase 4 is required for proper response to iron deficiency and to cadmium exposure. Plant Science, 209: 1-11. *co-first authors
 Jeandroz S., Lamotte O., Astier J., Rasul S., Trapet P., Besson-Bard A., Bourque S., Nicolas-Francès V., Wei M., Berkowitz G.A. and Wendehenne D. (2013) There's more to the picture than meets the eye: nitric oxide cross-talk with Ca2+ signaling. Plant Physiology, 163: 459-470.
 Koen E., Lamotte O., Besson-Bard A., Bourque S., Nicolas-Francès V., Jeandroz S. and Wendehenne D. (2013) Nitric oxide is a major player in plant immune system. Médecine/Sciences (Paris), 29: 309-316.
 Koen E., Szymańska K., Klinguer A., Dobrowolska G., Besson-Bard A. and Wendehenne D. (2012) Nitric oxide and glutathione impact the expression of iron uptake- and iron transport-related genes as well as the content of metals in A. thaliana plants grown under iron deficiency. Plant Signaling & Behavior, 7.
 Astier J., Besson-Bard A., Lamotte O., Bertoldo J., Bourque S., Terenzi H. and Wendehenne D. (2012) Nitric oxide inhibits the ATPase activity of the chaperone-like AAA+ATPase CDC48, a target for S-nitrosylation in cryptogein signaling in tobacco cells. Biochemical Journal, doi:10.1042/BJ20120257.
 Astier J., Kulik A., Koen E., Besson-Bard A., Bourque S., Jeandroz S., Lamotte O. and Wendehenne D. (2012) Protein S-nitrosylation: What's going on in plants? Free Radical Biology & Medicine, 53: 1101-1110.
 L’Haridon F., Besson-Bard A., Binda M., Serrano M., Abou-Mansour E., Balet F., Schoonbeek H.J., Hess S., Mir R., Leon J., Lamotte O. and Métraux J.P. (2011) A permeable cuticle is associated with the release of reactive oxygen species and induction of innate immunity. PLoS Pathogens, 7: e1002148.
 Astier J., Rasul S., Koen E., Manzoor H., Besson-Bard A., Lamotte O., Jeandroz S., Durner J., Lindermayr C. and Wendehenne D. (2011) S-nitrosylation: An emerging post-translational protein modification in plants. Plant Science, 181: 527-533.
 Besson-Bard A., Gravot A., Richaud P., Auroy P., Duc C., Gaymard F., Taconnat L., Renou J.-P., Pugin A. and Wendehenne D. (2009) Nitric oxide contributes to cadmium toxicity in Arabidopsis by promoting cadmium accumulation in roots and by up-regulating genes related to iron uptake. Plant Physiology, 149: 1302-1315.
 Besson-Bard A., Astier J., Rasul S., Wawer I., Dubreuil-Maurizi C., Jeandroz S. and Wendehenne D. (2009) Current view of nitric oxide-responsive genes in plants. Plant Science, 177: 302-309.
 Besson-Bard A., Griveau S., Bedioui F. and Wendehenne D. (2008) Real-time electrochemical detection of extracellular nitric oxide in tobacco cells exposed to cryptogein, an elicitor of defence responses. Journal of Experimental Botany, 59: 3407-3414.
 Besson-Bard A., Courtois C., Gauthier A., Dahan J., Dobrowolska G., Jeandroz S., Pugin A. and Wendehenne D. (2008) Nitric oxide in plants: production and cross-talk with Ca2+ signalling. Molecular Plant, 1: 218-228.
 Besson-Bard A., Pugin A. and Wendehenne D. (2008) New insights into nitric oxide signaling in plants. Annual Review of Plant Biology, 59: 21-39.
 Courtois C.*, Besson A.*, Dahan J., Bourque S., Dobrowolska G., Pugin A. and Wendehenne D. (2008) Nitric oxide signalling in plants: interplays with Ca2+ and protein kinases. Journal of Experimental Botany, 59: 155-163. *co-first authors
 Lamotte O., Courtois C., Dobrowolska G., Besson A., Pugin A. and Wendehenne D. (2006) Mechanisms of nitric-oxide-induced increase of free cytosolic Ca2+ concentration in Nicotiana plumbaginifolia cells. Free Radical Biology & Medicine, 40: 1369-1376.
 Larmonier N., Mérino D., Nicolas A., Cathelin D., Besson A., Bateman A., Solary E., Martin F., Katsanis E. and Bonnotte B. (2006) Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading. Apoptosis, 11(9): 1513-1524.

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