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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal UB AgroSup CNRS


ADRIAN Marielle

ADRIAN Marielle
Professeur en Sciences de la vigne - Université de Bourgogne
Pôle : IPM
Equipe/Thème : Immunité de la vigne: mécanismes et stimulation
Courriel :
Tel :

Curriculum Vitae

 - 1994: Master’s degree in Vine Science and Enology, University of Bordeaux, France
 - 1997: PhD in Phytopathology, University of Burgundy
 - 2005 : « Habilitation à Diriger les Recherches », University of Burgundy
 Scientific Career
 - Depuis 2015 : Director of the Vine and Wine Institute (IUVV) of the University of Burgundy
 - Depuis 2012 : Leader of the research group « induced resistance » (IPM team, Agroecology research unit) 
 - Depuis 2007 : Professeur of vine sciences – IUVV, University of Burgundy
 - 1998-2007 Associate professor in vine sciences – IUVV,  University of Burgundy
 - 1997-1998 :  Teaching and research contract (Agent Temporaire d’Enseignement et de Recherche, ATER)- IUVV, uB

Activités de Recherche

Our research group studies the induced resistance (IR) of plants -especially grapevine- against diseases by stimulation of their immune system. In this context, our research mainly includes:

-          identification of MAMPs and DAMPS (Molecular- and Damage- associated molecular patterns)-type oligosaccharide elicitors active as resistance inducers and the chemical characteristics (degree of polymerization, presence and nature of lateral chains) conferring their efficacy

-          identification of PRR-like receptors (Pattern Recognition Receptors) in grapevine

-          "metabolic" characterization of IR by global approaches (-omics) and targeted analyses (including volatile organic compounds) and research of  IR "markers".

-           study of factors able to modulate the plant responsiveness to IR (such as the stage of development, biostimulation and mycorrhiza)

The applied objective is to contribute to the development of IR in crop protection strategies.

We also study grapevine defence expression and metabolism evolution during compatible interactions (pathogens responsible for downy mildew and trunk diseases).

Activités d'enseignement

- about 200 hours /year CM, TD et TP.
 Grapevine Biology and physiology – cryptogamic diseases – Viticulture – Plant defence mechanisms
 - Diploma of the University of Burgundy: 3rd year bachelor grapevine sciences - 2nd year Master « Vine and Terroir” , National Diploma of Enologist (DNO)
 - Other diploma: OIV MSc in wine management (Montpellier Supagro), Mastère spécialisé en Commerce International des Vins et Spiritueux (Burgundy School of Business, Dijon), Mastère spécialisé en Connaissance et Commerce International des vins (Agrosup Dijon)


  • Gamm M., Héloir M.C., Adrian M. (2015). Trehalose and trehalose-6-phosphate induce stomatal movements and interfere with ABA-induced stomatal closure in grapevine. Journal International des Sciences de la Vigne et du Vin. In press
  • Paris F., Krzyżaniak Y., Gauvrit C., Jamois F., Domergue F., Joubès J., Ferrières V., Adrian M., Legentil L., Daire X., Trouvelot S. (2015). An ethoxylated surfactant enhances the penetration
of the sulfated laminarin through leaf cuticle and stomata, leading to increased induced resistance against grapevine downy mildew. Physiologia plantarum doi:10.1111/ppl.12394
  • Trouvelot S., Bonneau L., Redecker D., van Tuinen D., Adrian M., Wipf D. (2015). Arbuscular mycorrhiza symbiosis in viticulture. A review."Agronomy for Sustainable Development, DOI 10.1007/s13593-015-0329-7.
  • Guillier C., Gamm M., Lucchi G., Truntzer C., Pecqueur D., Adrian M., Héloir M.C. (2015). Towards the identification of two glycoproteins involved in the stomatal deregulation of downy mildew infected grapevine leaves. Molecular Plant Microbe Interactions, 28,11. 1227-1236.
  • Chalal M., Winkler J.B., Gourrat K., Trouvelot S., Adrian M., Schnitzler J.P., Jamois F., Daire X. (2015). Sesquiterpene VOCs are markers of elicitation by sulfated laminarine in grapevine. Frontiers in Plant Science, 6:350. doi: 10.3389/fpls.2015.00350.
  • Trouvelot S., Héloir M.C., Poinssot B., Gauthier A., Paris F., Guillier C., Combier M., Tdra L., Daire X., Adrian M. (2014). Carbohydrates in plant immunity and plant protection: roles and potential application as foliar sprays. Frontiers in Plant Science, doi: 10.3389/fpls.2014.00592
  • Lachhab N., Sanzani M., Adrian M., Chiltz A., Balacey S., Boselli M., Ippolito A., Poinssot B. (2014). Soybean and casein hydrolysates induce grapevine immune responses and resistance against Plasmopara viticola. Frontiers in Plant Science, 5, 716.  doi: 10.3389/fpls.2014.00716.
  • Chalal M., Klinguer A., Echairi A., Meunier P., Vervandier-Fasseur D., Adrian M. (2014). Antimicrobial activity of resveratrol analogues. Molecules, 19, 7679-7688.
  • Trdá L., Fernandez O., Boutrot F., Héloir M.C., Kelloniemi J., Daire X., Adrian M., Clément C., Zipfel C., Dorey S., Poinssot B. (2014). The grapevine flagellin receptor VvFLS2 differentially recognizes flagellin-derived epitopes from the endophytic growth-promoting bacterium Burkholderia phytofirmans and plant pathogenic bacteria. New Phytologist, DOI: 10.1111/nph.12592
  • Kim Khiook I.L., Schneider C., Heloir M.C., Bois B., Daire X., Adrian M., Trouvelot S. (2013). Image analysis methods for assessment of H2O2 production and Plasmopara viticola development in grapevine leaves: Application to the evaluation of resistance to downy mildew. Journal of Microbiological Methods, 28, 95(2), 235-244. doi: 10.1016/j.mimet.2013.08.012.
  • Steimetz E., Trouvelot S., Gindro K., Bordier A., Poinssot B., Adrian M., Daire X. (2012). Influence of leaf age on induced resistance in grapevine against Plasmopara viticola. Physiological and Molecular Plant Pathology, 79, 89-96.
  • Adrian M., Jeandet .P (2012). Effects of resveratrol on the ultrastructure of Botrytis cinerea conidia and biological significance in plant / pathogen interactions. Fitoterapia, 83, 1345-1350.
  • Gamm M., Héloir M.C., Bligny R., Vaillant-Gaveau N., Trouvelot S., Alcaraz G., Frettinger P., Clément C., Pugin A., Wendehenne D., Adrian M. (2011). Changes in carbohydrate metabolism in Plasmopara viticola -infected grapevine leaves. Molecular Plant Microbe Interactions. 24, 9, 1061-1073. doi:10.1094/MPMI -02-11-0040.
  • Gamm M., Héloir M.C., Kelloniemi J., Poinssot B., Wendehenne D., Adrian M. (2011). Identification and Validation of reference genes for gene expression normalization ingrapevine. Molecular Genetics and Genomics, DOI 10.1007/s00438-011-0607-2.
  • Allègre M., Héloir M.C., Trouvelot S., Daire X., Pugin A., Wendehenne D., Adrian M., (2009).
Are Grapevine Stomata Involved in the Elicitor-Induced Protection Against Downy Mildew?
Molecular Plant-Microbe Interactions, 22, 977-986.
  • Allègre M., Daire X., Héloir M.C., Trouvelot S., Mercier L., Adrian M., Pugin A. (2007). Stomatal deregulation in Plasmopara viticola-infected grapevine leaves. New Phytologist, 173, 832-840.
  • Lesniewska E. / Adrian M., Klinger A., Pugin  A. (2004). Cell wall modification in grapevine cells in response to UV stress investigated by atomic force microscopy. Ultramicroscopy, 100, 171-178.
  • Borie B., Jeandet P., Bessis R., Adrian M. (2003). Comparison of resveratrol and stilbene synthase mRNA production from grapevine leaves treated with biotic and abiotic phytoalexin elicitors. American Journal of Enology and Viticulture, 55,1,60-64.
  • Poussier M., Guilloux-Benatier M., Torres M., Heras E., Adrian M. (2003). Influence of different maceration techniques and microorganism enzymatic activities on wine stilbene content. American Journal of Enology and Viticulture, 54,4, 261-266.
  • Aziz A. /Poinssot B., Daire X., Adrian M., Bézier A., Joubert J.M., Pugin A. (2003). Laminarin elicits defence responses in grapevine and induced protection against Botrytis cinerea and Plasmopara viticola. Molecular Plant Microbe Interaction, 16,12, 1118-1128.
  • Poinssot B., Vandelle E., Bentéjac M., Adrian M., Levis C., Brygoo Y., Garijn J., Sicilia F., Coutos-Thévenot P., Pugin A. (2003). The endopolygalacturonase 1 from Botrytis cinerea activates grapevine defence reactions unrelated to its enzymatic activity. Molecular Plant Microbe Interaction, 16, 6, 553-564.
  • Jeandet P., Douillet-Breuil A.C., Bessis R., Debord S., Sbaghi M., Adrian M. (2002). Phytoalexins from the Vitaceae : biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity and metabolism. Journal of Agricultural and Food Chemistry, 50, 10, 2731-2741.
  • Moriartry J.M., Harmon R., Weston L.A., Bessis R., Breuil A.C., Adrian M., Jeandet P. (2001). Resveratrol content of two Californian table grape cultivars. Vitis, 40,1, 43-44.
  • Adrian M., Jeandet P., Douillet-Breuil A.C., Tesson L., Bessis R. (2000). Stilbene content of mature Vitis vinifera berries in response to UV-C elicitation. Journal of Agricultural and Food Chemistry, 48, 12, 6103-6105.
  • Adrian M., Jeandet P., Breuil A.C., Levite D., Debord S., Bessis R. (2000). Assay of resveratrol and derivative stilbenes in wines by direct injection high performance liquid chromatography. American Journal of Enology and Viticulture, 51,1, 37-41.
  • Douillet-Breuil A.C., Jeandet P., Adrian M., Bessis R. (1999). Changes in the phytoalexin content of various Vitis spp. in response to UV-C elicitation. Journal of Agricultural and Food Chemistry, 47, 10, 4456-4461.
  • Breuil A.C., Jeandet P., Adrian M., Chopin F., Pirio N., Meunier P., Bessis R. (1999). Characterization of a pterostilbene dehydrodimer produced by laccase of Botrytis cinerea. Phytopathology, 89, 4, 298-302.
  • Breuil A.C., Adrian M., Pirio N., Weston L.A., Meunier P., Bessis R., Jeandet P. (1998). Metabolism of stilbene phytoalexins by Botrytis cinerea : characterization of a resveratrol dehydrodimer. Tetrahedron Letters, 39, 537-540.
  • Adrian M., Rajaei H., Jeandet P., Veneau J., Bessis R. (1998). Resveratrol oxidation in Botrytis cinerea conidia. Phytopathology, 88, 5, 472-476.
  • Jeandet P., Breuil A.C., Adrian M., Weston L.A., Meunier P., Maume G., Bessis R. (1997). HPLC analysis of stilbene phytoalexins coupling photodiode array detection and fluorimetry.  Analytical Chemistry, 69, 24, 5172-5177.
  • Adrian M., Jeandet P., Veneau J., Weston L.A., Bessis R. (1997). Biological activity of resveratrol, a stilbenic compound from grapevines, on Botrytis cinerea, the causal agent for gray mold. Journal of Chemical Ecology, 23, 1689-1702.
  • Adrian M., Jeandet P., Joubert J.M., Bessis R. (1996). Induction of phytoalexin (resveratrol) synthesis in grapevine leaves treated with aluminum chloride (AlCl3). Journal of Agricultural and Food Chemistry, 44, 8, 1979-1981.
  • Adrian M., Fournioux J.C., Bessis R. (1995). In vitro morphogenesis of grapevine (Vitis vinifera  L.) originated from anticipated or latent buds. Vitis, 35, 3, 107-111.


Jeandet P., Bessis R., Adrian M., Joubert J.M., Yvin J.C. 1995 - Use of aluminum chloride as a resveratrol formation elicitor in plants.
1997 – extension internationale: PCT Int. Appl. WO 97 18,715.

Liens externes


Mots clés

Vigne, défenses, résistance induite, éliciteurs, immunité,  PRR, Interaction, métabolites

Principaux contacts

Manager of projects: FUI - Conseil Régional de Bourgogne / Bureau Interprofessionnel des Vins de Bourgogne / Chambre d’agriculture de Bourgogne and Yonne

Involved in KBBE, ANR, Casdar, France Agrimer, CIVB (Conseil Interprofessionnel des Vins de Bordeaux) / Chambre d’agriculture de la Gironde projects and partnerships with companies